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Biological dose estimation model for heavy ions

In general, the relative biological effectiveness (RBE) of high-energy heavy ions (HZE particle) is expressed as a function of their LET. However, RBE of HZE particles cannot be uniquely determined from their LET because of their large production cross sections of high-energy delta-rays. Hence, it is severely requested to develop a biological dose estimation model that can explicitly consider the track structure of delta-rays around the trajectory of HZE particle. We therefore developed a biological dose estimation method of HZE particles based on the lineal energy y distribution.

References
[1] T. Sato et al., Int. J. Radiat. Oncol. Biol. Phys. Ahead-of-print (2022).
[2] T. Sato et al., Radiat. Prot. Dosim. 183, 247-250 (2019).
[3] T. Sato et al., Sci. Rep. 8, 988 (2018)
[4] T. Sato et al., PLOS ONE 9(11), e114056 (2014)
[5] T. Sato et al,, PLOS ONE 9(6), e99831 (2014)
[6] T. Sato et al., Radiat. Res. 178, 341-356 (2012)
[7] T. Sato et al., Int. J. Radiat. Biol.88, 143-150 (2012)
[8] T. Sato et al., Prot. Dosim. 143, 491-496 (2011)
[9] T. Sato et al., Radiat. Res. 171, 107-117 (2009)
[10] T. Sato et al., Radiat. Prot. Dosim. 122, 41-45 (2006).


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